Evidence-Based Complementary and Alternative Medicine / 2020 / Article / Tab 3 / Research Article
In Vitro Cytotoxic Activity against Breast, Cervical, and Ovarian Cancer Cells and Flavonoid Content of Plant Ingredients Used in a Selected Thai Traditional Cancer Remedy: Correlation and Hierarchical Cluster AnalysisTable 3 Selectivity index (SI) of cytotoxic activity and total flavonoid content of the plant and remedy extracts.
Plant extracts Selectivity index (SI) Total flavonoid (mean ± SEM; mg quercetin eq./g) HaCat/MCF7 ratio HaCat/SKOV3 ratio HaCat/Hela ratio A. ebracteatus 0.81 3.76 3.20 151.32 ± 3.59 A. galanga 2.68 2.76 2.67 140.84 ± 4.47 A. villosum 1.70 0.65 0.88 79.72 ± 7.94 A. comosus 1.00 1.00 1.00 75.07 ± 4.14 A. paniculata 0.44 0.38 0.38 96.1 ± 5.87 A. sinensis 2.09 0.80 0.99 246.56 ± 2.58 A. dahurica 10.13 1.00 1.00 227.95 ± 5.69 A. valgaris 0.56 0.77 0.59 64.83 ± 3.47 A. membranaceus 1.00 1.00 1.00 185.91 ± 6.78 B. rotunda 1.14 0.98 0.57 175.38 ± 5.19 C. halicacalum 2.19 1.00 1.00 138.29 ± 3.98 C. papaya 2.37 1.00 1.00 134.27 ± 2.61 C. verum 2.21 1.00 1.91 220.97 ± 4.12 C myrrha 1.00 1.00 1.45 143.77 ± 4.37 C. stellatopilosus 0.39 0.34 0.34 46.38 ± 5.02 C. aromatic 0.10 0.09 0.09 259.7 ± 3.21 C. Comosa 0.57 0.64 0.54 139.28 ± 3.04 D. opposite 1.00 1.00 1.00 113.73 ± 5.71 E. acoroides 1.00 1.00 1.00 31.96 ± 2.29 F. albopurpurea 6.83 1.00 1.00 25.47 ± 2.13 F. vulgare 4.92 2.21 1.47 81.57 ± 2.97 H. indicum 3.39 2.85 2.09 33.64 ± 2.61 E. arvense 1.00 1.00 1.00 33.25 ± 2.42 J. sambac 1.00 1.00 1.00 30.06 ± 2.73 K. galanga 2.03 1.00 1.00 88.23 ± 2.71 L. triadra 0.82 1.76 0.82 136.84 ± 2.68 L. striatum 3.31 3.53 2.76 34.39 ± 3.07 L. barbarum. 1.00 1.00 1.00 85.6 ± 2.98 M. cochinchinensis 0.71 0.38 0.38 93.77 ± 3.4 M. siamensis 2.97 0.33 0.33 204.94 ± 2.72 M. ferrea 0.08 0.07 0.07 216.49 ± 7.31 M. elengi 1.00 1.00 1.00 190.5 ± 3.54 M. fragrans 0.51 0.33 0.33 72.23 ± 3.59 N. nucifera 1.00 1.00 1.00 82.43 ± 2.53 O. tenuiflorum 1.88 0.95 0.95 124.35 ± 2.74 P. amarus 3.24 2.61 2.14 164.6 ± 6.21 P. cablin 4.06 1.00 1.00 73.58 ± 4.98 R. glutinosa 1.00 1.00 1.00 101.58 ± 2.06 R. nasutus 1.52 2.07 1.00 183.57 ± 5.46 S. chinensis. 1.00 1.00 1.00 94.79 ± 5.57 S. indicum 1.00 1.00 1.00 163.17 ± 3.44 T. indica 6.27 0.93 0.93 158 ± 5.50 V. vinifera 1.00 1.00 1.00 14.8 ± 2.73 TTW 0.47 0.47 0.47 41.92 ± 4.04 TTE 1.91 1.00 1.00 105.67 ± 4.33