Research Article

In Vitro Cytotoxic Activity against Breast, Cervical, and Ovarian Cancer Cells and Flavonoid Content of Plant Ingredients Used in a Selected Thai Traditional Cancer Remedy: Correlation and Hierarchical Cluster Analysis

Table 3

Selectivity index (SI) of cytotoxic activity and total flavonoid content of the plant and remedy extracts.

Plant extractsSelectivity index (SI)Total flavonoid (mean ± SEM; mg quercetin eq./g)
HaCat/MCF7 ratioHaCat/SKOV3 ratioHaCat/Hela ratio

A. ebracteatus0.813.763.20151.32 ± 3.59
A. galanga2.682.762.67140.84 ± 4.47
A. villosum1.700.650.8879.72 ± 7.94
A. comosus1.001.001.0075.07 ± 4.14
A. paniculata0.440.380.3896.1 ± 5.87
A. sinensis2.090.800.99246.56 ± 2.58
A. dahurica10.131.001.00227.95 ± 5.69
A. valgaris0.560.770.5964.83 ± 3.47
A. membranaceus1.001.001.00185.91 ± 6.78
B. rotunda1.140.980.57175.38 ± 5.19
C. halicacalum2.191.001.00138.29 ± 3.98
C. papaya2.371.001.00134.27 ± 2.61
C. verum2.211.001.91220.97 ± 4.12
C myrrha1.001.001.45143.77 ± 4.37
C. stellatopilosus0.390.340.3446.38 ± 5.02
C. aromatic0.100.090.09259.7 ± 3.21
C. Comosa0.570.640.54139.28 ± 3.04
D. opposite1.001.001.00113.73 ± 5.71
E. acoroides1.001.001.0031.96 ± 2.29
F. albopurpurea6.831.001.0025.47 ± 2.13
F. vulgare4.922.211.4781.57 ± 2.97
H. indicum3.392.852.0933.64 ± 2.61
E. arvense1.001.001.0033.25 ± 2.42
J. sambac1.001.001.0030.06 ± 2.73
K. galanga2.031.001.0088.23 ± 2.71
L. triadra0.821.760.82136.84 ± 2.68
L. striatum3.313.532.7634.39 ± 3.07
L. barbarum.1.001.001.0085.6 ± 2.98
M. cochinchinensis0.710.380.3893.77 ± 3.4
M. siamensis2.970.330.33204.94 ± 2.72
M. ferrea0.080.070.07216.49 ± 7.31
M. elengi1.001.001.00190.5 ± 3.54
M. fragrans0.510.330.3372.23 ± 3.59
N. nucifera1.001.001.0082.43 ± 2.53
O. tenuiflorum1.880.950.95124.35 ± 2.74
P. amarus3.242.612.14164.6 ± 6.21
P. cablin4.061.001.0073.58 ± 4.98
R. glutinosa1.001.001.00101.58 ± 2.06
R. nasutus1.522.071.00183.57 ± 5.46
S. chinensis.1.001.001.0094.79 ± 5.57
S. indicum1.001.001.00163.17 ± 3.44
T. indica6.270.930.93158 ± 5.50
V. vinifera1.001.001.0014.8 ± 2.73
TTW0.470.470.4741.92 ± 4.04
TTE1.911.001.00105.67 ± 4.33