Kang-Xian Pills Inhibit Inflammatory Response and Decrease Gut Permeability to Treat Carbon Tetrachloride-Induced Chronic Hepatic Injury through Modulating Gut Microbiota

Figure 2

KX treatment improved the pathological changes in CHI model mice. (a, b) KX treatment increased the body weight and liver index CHI model mice. (c) H&E staining indicated that KX treatment ameliorated the inflammatory cells infiltration and cellular swelling of hepatocytes. Black arrows indicate the inflammatory cell infiltration. Red arrows indicate the cellular swelling of hepatocytes. (d, f) Masson staining indicated that KX treatment decreased the collagen deposition in the liver. (e, g) Immunostaining indicated that KX treatment decreased the levels of α-SMA in the liver (100x). Control, Model, and KX groups (n = 10 per group). Data are presented as mean ± SD. ^## compared with the Control group; compared with the Model group; compared with the Model group.

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