Research Article

Evaluation of Antidiabetic Activity of the Leaf Latex of Aloe pulcherrima Gilbert and Sebsebe (Aloaceae)

Table 3

Effect of the leaf latex of A. pulcherrima on the glucose tolerance test in mice.

GroupsBlood glucose level (mg/dl)
0 h0.5 h1 h2 h

10ml/kg vehicle89.13 ± 0.31156.95 ± 0.67142.85 ± 0.55125.51 ± 0.81
5 mg/kg glibenclamide88.37 ± 1.19157.23 ± 0.71114.68 ± 1.33a391.47 ± 0.27a3
200 mg/kg·LL89.33 ± 0.45158.24 ± 1.31129.57 ± 0.61107.50 ± 1.09a2
400 mg/kg·LL87.67 ± 0.26159.12 ± 0.29120.28 ± 0.72a398.61 ± 0.37a3
600 mg/kg·LL90.21 ± 1.22157.87 ± 0.51118.25 ± 0.27a394.72 ± 0.51a3

The result is presented as mean ± standard error of the mean, n = 6; acompared to vehicle; 1; 2; LL, leaf latex.