Research Article

Evaluation of Antidiabetic Activity of the Leaf Latex of Aloe pulcherrima Gilbert and Sebsebe (Aloaceae)

Table 5

The effect of the latex of Aloe pulcherrima on body weight of diabetic mice.

GroupsBW (gram)
PretreatmentWeek oneWeek two

10 ml/kg vehicle NC27.82 ± 0.3228.64 ± 0.3828.94 ± 0.38
10 ml/kg vehicle DC24.59 ± 0.5923.08 ± 0.7422.94 ± 0.45
5 mg/kg glibenclamide24.23 ± 0.5328.76 ± 0.56a328.87 ± 0.36 a3
200 mg/kg·LL23.19 ± 0.6526.65 ± 0.49 a126.15 ± 0.43 a1
400 mg/kg·LL23.47 ± 0.6326.91 ± 0.60 a127.23 ± 0.61 a1
600 mg/kg·LL25.07 ± 0.3327.72 ± 0.34 a127.82 ± 0.35 a1

The result is expressed as mean ± standard error of the mean, n = 6; acompared to diabetic control; 1; 2. BW, body weight; DC, diabetic control; LL, leaf latex; NC, normal control.