Polysaccharides of Scrophularia ningpoensis Hemsl.: Extraction, Antioxidant, and Anti-Inflammatory Evaluation

Figure 6

Anti-inflammatory activities of SNPS on LPS-induced mice. Mice were treated with SNPS (100, 200, and 400 mg/kg), aspirin (10 mg/kg), or saline for 4 days (once per day) and stimulated with LPS (1 mg/kg) for 90 min. The protein expression of (a) IL-6 and (b) in serum were determined by ELISA. Values are means ± S.E. (n = 6). The mRNA expression of IL-6 (c) and TNF-α (d) in the liver was measured using real-time RT-PCR. Values are means ± S.E. ((n) = 4). The β-actin was used as an internal control for real-time RT-PCR. Aspirin was used as a positive control. The significant difference compared with the normal control group, . The significant difference compared with LPS-treated alone, , , .

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