Antimalarial Activity of Meriandra dianthera Leaf Extracts in Plasmodium berghei-Infected Mice

Table 1

Effect of the hydromethanolic leaf extract of M. dianthera on mean parasitaemia level and mean survival time of P. berghei-infected mice.

Test sample	Dose (mg/kg)	% of parasitaemia	% of suppression	MST (days)
NC	10 ml/kg	44.10 ± 1.82	0.00	7.00 ± 00
Extract	200	38.43 ± 3.25^c	14	7.83 ± 0.31
Extract	400	25.77 ± 2.41^a^c	42.28	8.33 ± 0.33^a
Extract	600	23.02 ± 1.88^abc	45.52	8.67 ± 0.33^a
CQ	25	00 ± 00^a	100	ND

Results are presented as mean ± SEM; n = 6; ^awhen compared to negative control (NC); ^bwhen compared to 200 mg/kg of the extract; ^cwhen compared to CQ treated group; ; ; CQ = chloroquine phosphate; ND = no death within the follow-up period; MST = mean survival time in days.