Evidence-Based Complementary and Alternative Medicine

Research Article

Antiangiogenesis Roles of Exosomes with Fei-Liu-Ping Ointment Treatment are Involved in the Lung Carcinoma with the Lewis Xenograft Mouse Model

Table 2

Components of FLP ointment identified by UHPLC-Orbitrap MS.


No.	t_R	Precursor ion (m/z)		Diff. (ppm)	Elem. Comp.	Identification

1	1.27	[M + Na]⁺	365.1047	−2.061	C₁₂H₂₂O₁₁Na	Maltose
2	1.27	[M + Na]⁺	365.1047	−1.946	C₁₈H₃₂O₁₆Na	D-Melezitose
3	1.27	[M + Na]⁺	509.1468	−1.829	C₁₈H₃₀O₁₅Na	Beta-glucan
4	1.35	[M + H]⁺	305.1333	−3.269	C₁₂H₂₁N₂O₇	2′-Deoxymugineic acid
5	2.59	[M + H]⁺	145.0493	−1.898	C₆H₉O₄	Monoethyl fumarate
6	3.21	[M + H]⁺	127.0387	−2.130	C₆H₇O₃	5-Hydroxymethylfurfural
7	4.35	[M + H]⁺	163.0368	−2.150	C₉H₇O₃	Umbelliferone
8	13.74	[M + Na]⁺	447.1277	3.337	C₂₀H₂₄O₁₀Na	Praeroside II
9	13.74	[M + Na]⁺	469.1094	−2.298	C₂₂H₂₂O₁₀Na	Calycosin-7-O-beta-D-glucoside
10	15.31	[M + Na]⁺	463.0862	3.332	C₁₉H₂₀O₁₂Na	4-O-(E)-Caffeoyl-5-O-malonylquinic acid
11	15.84	[M + Na]⁺	491.2454	−1.879	C₂₁H₄₀O₁₁Na	2,6-Dimethyl-4-heptyl-β-D-maltopyranoside
12	17.76	[M + Na]⁺	447.0914	−1.695	C₁₉H₂₀O₁₁Na	6-O-galloylarbutin
13	18.18	[M + H]⁺	771.4877	−1.541	C₄₁H₇₁O₁₃	Ginsenoside F3
14	18.29	[M + H]⁺	639.4451	−2.486	C₃₆H₆₃O₉	Ginsenoside F1
15	18.40	[M + H]⁺	621.4347	−2.261	C₃₆H₆₁O₈	Ginsenoside Rh4
16	19.47	[M + H]⁺	639.4455	−1.814	C₃₆H₆₃O₉	Ginsenoside Rh1
17	19.47	[M + H]⁺	785.5029	−2.162	C₄₂H₇₃O₁₃	Ginsenoside Rg3
18	19.79	[M + H]⁺	419.1329	−1.810	C₂₁H₂₃O₉	Liquiritin
19	19.90	[M + H]⁺	489.1383		C₂₄H₂₅O₁₁	Kaempferide, 7-O-(4-O-acetyl-α-L-rhamnopyranosyl)
20	20.01	[M + H]⁺	431.1328	−2.038	C₂₂H₂₃O₉	Ononin
21	20.97	[M + Na]⁺	471.2195	−1.249	C₂₁H₃₆O₁₀Na	Geranyl b-primeveroside
22	20.97	[M + Na]⁺	823.4806	−1.017	C₄₂H₇₂O₁₄Na	Ginsenoside Rg1
23	21.19	[M + Na]⁺	969.5375	−1.853	C₄₈H₈₂O₁₈Na	Ginsenoside Re
24	21.94	[M + Na]⁺	485.1410	−1.707	C₂₃H₂₆O₁₀Na	Astrapterocarpan
25	22.15	[M + H]⁺	285.0752	−1.824	C₁₆H₁₃O₅	Calycosin
26	22.25	[M + H]⁺	167.0700	−1.860	C₉H₁₁O₃	(R)-(-)-methyl mandelate
27	22.56	[M + H]⁺	539.1852	−2.094	C₂₈H₃₃O₁₄	Luteolin-7-O-rutinoside
28	22.77	[M + H]⁺	1007.5046	−1.161	C₄₈H₇₈O₂₂	Aesculuside B
29	22.99	[M + Na]⁺	487.1565	−1.946	C₂₃H₂₈O₁₀Na	7,2′-Dihydroxy-3′,4′-dimethoxyisoflavane-7-O-glucoside
30	24.70	[M + H]⁺	1093.5400	−2.277	C₅₂H₈₅O₂₄	Deapioplatycodin D
31	25.35	[M + H]⁺	845.4517	−1.498	C₄₂H₆₉O₁₇	Saniculoside A
32	25.88	[M + H]⁺	639.4456	−1.626	C₃₆H₆₃O₉	Sanchinoside B1
33	27.17	[M + H]⁺	947.5196	−1.495	C₄₇H₇₉O₁₉	Astragaloside VI
34	27.81	[M + H]⁺	801.4976	−2.399	C₄₂H₇₃O₁₄	Ginsenoside Rg1
35	28.55	[M + H]⁺	855.3994	−1.802	C₄₂H₆₃O₁₈	22-Hydroxyl-licorice-saponin G2
36	28.55	[M + H]⁺	423.3216	−1.774	C₃₀H₄₅O₅	(R)-4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,8a,9,10,11,12,12a,14b-hexadecahydro-picen-3-ol
37	28.77	[M + H]⁺	683.3992	−1.366	C₃₆H₅₉O₁₂	3-O-β-glucosyl-platycodigenin
38	28.98	[M + H]⁺	315.1221	−1.905	C₁₈H₁₉O₅	Agrimonolide
39	28.98	[M + H]⁺	477.1745	−2.208	C₂₄H₂₉O₁₀	Agrimonolide-6-O-glucopyranoside
40	29.19	[M + Na]⁺	1131.5902	−1.723	C₅₄H₉₂O₂₃Na	Ginsenoside Rb1
41	29.40	[M + H]⁺	269.0804	−1.469	C₁₆H₁₃O₄	Formononetin
42	30.45	[M + Na]⁺	807.4486	−1.880	C₄₁H₆₈O₁₄Na	Astragaloside III
43	31.40	[M + H]⁺	839.4070	−1.569	C₄₂H₆₃O₁₇	22-Hydroxyl-glycyrrhizin
44	31.82	[M + Na]⁺	849.4584	−2.734	C₄₃H₇₀O₁₅Na	Isoastragalosides II
45	32.34	[M + H]⁺	823.4097	−1.618	C₄₆H₆₃O₁₆	Glycyrrhizinic acid
46	32.34	[M + H]⁺	647.3776	−2.092	C₃₆H₅₄O₁₀	Glycyrrhizinic acid 3-O-glucuronide
47	33.07	[M + H]⁺	785.5032	−1.704	C₄₂H₇₃O₁₃	Ginsenoside Rg3
48	35.26	[M + H]⁺	647.3779	−1.706	C₃₆H₅₅O₁₀	Glycyrrhetinic acid monoglucuronide
49	35.26	[M + Na]⁺	891.4695	−1.926	C₄₅H₇₂O₁₆Na	Isoastragaloside I
50	38.36	[M + H]⁺	425.3771	−1.605	C₃₀H₄₉O	Pachysandienol-A
51	38.36	[M + Na]⁺	789.4744	−2.000	C₄₂H₇₀O₁₂Na	Ginsenoside Rg5
52	39.72	[M + H]⁺	277.1795	−1.050	C₁₇H₂₅O₃	Cyclandelate
53	40.23	[M + H]⁺	471.3463	−1.159	C₃₀H₄₇O₄	Glycyrrhetinate