Research Article

Xiao-Qing-Long-Tang Maintains Cardiac Function during Heart Failure with Reduced Ejection Fraction in Salt-Sensitive Rats by Regulating the Imbalance of Cardiac Sympathetic Innervation

Figure 5

XQLT improved the functional dominance of sympathetic nerves. (a) Double immunofluorescence of TH+/CHAT + positive fibers in the left ventricle (scale bars: 50 μm). (b) Relative TH+/CHAT + positive fibers area. (c) Representative Western blot of myocardial TH and CHAT. (d) and (e) Relative protein levels of TH and CHAT were calculated by band intensity against β-actin. (f) The SGVs and SAGVs of left ventricles by transmission electron microscopy (black arrows indicate the SGV and white arrows indicate the SAGV, scale bars: 500 nm). Quantitative data are shown as the mean ± SD, n = 9.  < 0.01,  < 0.01 vs. the SS-13BN group;  < 0.05 vs. the DS group.
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