Research Article
Shikonin Inhibits Der p 2-Induced Cytokine and Chemokine Expression in Dendritic Cells in Patients with Atopic Dermatitis
Table 5
Proinflammatory cytokine level of the Der p 2 group and dexamethasone-treated group (n = 6).
| | Der p 2 | Dexamethasone | value | | Mean | SD | Mean | SD |
| | IL-4 | 0.5 | ±0.4 | 0.3 | ±0.1 | 0.068 | | IL-5 | 0.7 | ±1.7 | 0.4 | ±1.1 | 0.317 | | IL-6 | 3.3 | ±4.1 | 0.7 | ±0.7 | 0.027 | | IL-9 | 21.6 | ±22.6 | 21.9 | ±17.3 | 0.463 | | IL-13 | 1.3 | ±2.2 | 3.6 | ±4.5 | 0.080 | | IL-17A | 12.1 | ±9.6 | 6.7 | ±4.1 | 0.046 | | MCP-1 | 91.0 | ±112.9 | 32.5 | ±37.9 | 0.028 | | MIP-1α | 330.6 | ±505.5 | 21.8 | ±25.2 | 0.028 | | MIP-1β | 610.2 | ±919.4 | 147.7 | ±173.9 | 0.116 | | RANTES | 29.8 | ±36.4 | 8.2 | ±6.0 | 0.028 |
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Data are expressed as the mean ± standard deviation (SD). Data were analyzed using the Wilcoxon signed-rank test.
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