Research Article

Resveratrol Treatment Is Associated with Lipid Regulation and Inhibition of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) in Rabbits Fed a High-Fat Diet

Table 1

Biochemical analysis of rabbits from NDG (n = 8), FDG (n = 8), and RFG (n = 8) analyzed before the beginning of the fat diet (baseline).

NDG (n = 8)FDG (n = 8)RFG (n = 8)F value

Weight (kg)0.96 ± 0.050.99 ± 0.081.01 ± 0.080.9030.420
ALT43.20 ± 9.6541.22 ± 8.8344.76 ± 12.800.2260.800
AST36.38 ± 8.6133.73 ± 5.9134.88 ± 4.980.3170.732
CREA67.94 ± 8.3964.72 ± 6.2765.75 ± 9.690.3180.731
TG0.63 ± 0.200.50 ± 0.160.48 ± 0.072.2300.132
TC1.94 ± 0.211.88 ± 0.281.99 ± 0.430.2400.789
HDL-C0.93 ± 0.190.94 ± 0.250.93 ± 0.170.0060.994
LDL-C0.84 ± 0.220.95 ± 0.120.80 ± 0.271.0530.367
Lp-PLA2#461.50 ± 89.57525.48 ± 32.50494.88 ± 32.562.4240.113

#The test result of homogeneity of variance was , and Dunnett’s T method was used for multiple comparison of value correction, while the Bonferroni method was used for the other indicators. NDG, normal diet group; FDG, fat diet group; RFG, fat diet with resveratrol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CREA, creatinine; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Lp-PLA2, lipoprotein-associated phospholipase A2.