Evidence-Based Complementary and Alternative Medicine

Research Article

Resveratrol Treatment Is Associated with Lipid Regulation and Inhibition of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) in Rabbits Fed a High-Fat Diet

Table 3

Biochemical analysis of rabbits from RFG (n = 8) before the beginning of the treatment with fat diet and at the end of the 3-month fat diet.


	Baseline (n = 8)	After 3 months (n = 8)	t	value

Weight(kg) (NDG)	0.96 ± 0.05	2.90 ± 0.08	−73.655	<0.001
Weight (kg) (FDG)	0.99 ± 0.08	2.98 ± 0.15	−49.925	<0.001
Weight (kg) (RFG)	1.01 ± 0.08	2.96 ± 0.07	−39.000	<0.001
ALT (NDG)	43.20 ± 9.65	44.81 ± 7.95	−0.781	0.461
ALT (FDG)	41.22 ± 8.83	50.86 ± 24.53	−1.172	0.280
ALT (RFG)	44.76 ± 12.80	61.06 ± 20.26	−2.160	0.068
AST (NDG)	36.38 ± 8.61	40.51 ± 6.46	−2.490	0.042
AST (FDG)	33.73 ± 5.91	84.32 ± 54.94	−2.639	0.033
AST (RFG)	34.88 ± 4.98	77.91 ± 24.54	−5.587	0.001
CREA (NDG)	67.94 ± 8.39	77.38 ± 10.45	−7.002	<0.001
CREA (FDG)	64.72 ± 6.27	111.92 ± 11.38	−10.794	<0.001
CREA (RFG)	65.75 ± 9.69	127.63 ± 10.84	−12.390	<0.001
TG (NDG)	0.63 ± 0.20	0.62 ± 0.21	0.086	0.934
TG (FDG)	0.50 ± 0.16	0.90 ± 0.42	−2.230	0.061
TG (RFG)	0.48 ± 0.07	0.76 ± 0.28	−2.986	0.020
TC (NDG)	1.94 ± 0.21	2.19 ± 0.30	−2.919	0.022
TC (FDG)	1.88 ± 0.28	30.32 ± 5.74	−14.078	<0.001
TC (RFG)	1.99 ± 0.43	11.84 ± 2.78	−9.275	<0.001
HDL (NDG)	0.93 ± 0.19	1.03 ± 0.20	−3.359	0.012
HDL (FDG)	0.94 ± 0.25	3.28 ± 1.61	−3.815	0.007
HDL (RFG)	0.93 ± 0.17	1.58 ± 0.35	−4.880	0.002
LDL (NDG)	0.84 ± 0.22	0.91 ± 0.22	−1.270	0.245
LDL (FDG)	0.95 ± 0.12	16.45 ± 3.16	−13.489	<0.001
LDL (RFG)	0.80 ± 0.27	6.23 ± 1.53	−9.221	<0.001
Lp-PLA2^# (NDG)	461.50 ± 89.57	520.14 ± 51.55	−1.930	0.095
Lp-PLA2^# (FDG)	525.48 ± 32.50	1928.88 ± 385.78	−10.090	<0.001
Lp-PLA2^# (RFG)	494.88 ± 32.56	953.20 ± 96.66	−12.816	<0.001

^#The test result of homogeneity of variance was , and Dunnett’s T method was used for multiple comparison of value correction, while the Bonferroni method was used for the other indicators. NDG, normal diet group; FDG, fat diet group; RFG, fat diet with resveratrol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CREA, creatinine; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Lp-PLA2, lipoprotein-associated phospholipase A2.