In Vivo Evaluation of Wound Healing and Anti-Inflammatory Activity of 80% Methanol Crude Flower Extract of Hagenia abyssinica (Bruce) J.F. Gmel in Mice

Table 5

Activity of the 80% methanolic crude extracts ointment of the flowers of H. abyssinica on period of epithelialization (number of days).

Treatment group	Period of epithelization (days), mean ± SEM	% decrease in epithelization period
SO	18.67 ± 0.67	—
NF	13.00 ± 0.45^a3	30.37%
5% CFEO	14.67 ± 0.42^a3	21.42%
10% CFEO	12.67 ± 0.42^a3	32.14%

Values are expressed as mean ± SEM (n = 6 mice in each group) and analyzed by one-way ANOVA followed by the post hoc Tukey test; ^acompared to the negative control; ³; SO = simple ointment; NF = nitrofurazone 0.2% ointment; CEO = crude flower extract.