In Vivo Evaluation of Wound Healing and Anti-Inflammatory Activity of 80% Methanol Crude Flower Extract of Hagenia abyssinica (Bruce) J.F. Gmel in Mice

Table 6

Activity of the solvent fraction extract ointment of the flowers of H. abyssinica on period of epithelialization (number of days).

Treatment group	Period of epithelization (day), mean ± SEM	% decrease in epithelization period
SO	18.33 ± 0.61	—
NF	14.67 ± 0.42^a2	20.00
5% AQFO	15.67 ± 0.613^a1	14.51
10% AQFO	14.67 ± 0.42^a2	20.00
5% CHF	16.33 ± 0.61	10.91
10% CHFO	15.67 ± 0.61^a1	14.51
5% EAFO	15.33 ± 0.42^a2	16.37
10% EAFO	14.00 ± 0.52^a3	23.62

Values are expressed as mean ± SEM (n = 6 mice in each group) and analyzed by one-way ANOVA followed by the post hoc Tukey test; ^acompared to the SO; ¹; ²; ³; AQFO = aqueous fraction ointment; CHFO = chloroform fraction ointment; EAFO = ethylacetate fraction ointment; NF = nitrofurazone 0.2% ointment; SO = simple ointment.