Evidence-Based Complementary and Alternative Medicine

Research Article

Inhibition of HIV-1 Protease by Carpobrotus edulis (L.)

Table 2

Putative identification of compounds in C. edulis showing the main parameters for their identification.


Class of compounds	Putative identification	Mass	m/z	Adduct	RT (min)	δ (ppm)	Formula

Flavonoids	Di-ethoxydimethylphosphoramide	211.202	211.108	[M-P]^-	0.5	3.2	C₆H₁₈N₃O₃P
Flavonoids	Dimethyl-2-(2-nitrophenoxy)ethyl-azanium	211.241	211.107	[M-H]^-	0.5	3.2	C₁₀H₁₅N₂O₃

Phenolic acids	N,N′-Dicyclohexyl-4-morpholinecarboxamidine	293.455	293.246	[M-H]^-	14.0	1.7	C₁₇H₃₁N₃O
	N-(2-Morpholin-4-ylethyl)-4-(1,3-thiazol 2-ylmethyl)-1,4-diazepane-1-carbothioamide	369.546	369.165	[M-H]^-	4.5	3.2	C₁₆H₁₀N₉O₂
	1-(4-Amino-1,2,5-oxadiazol-3-yl)-N-(4-dimethylaminophenyl)methylideneamino-5-ethyltriazole-4-carboxamide	369.389	309.131	[M-H]^-	1.5	5.0	C₁₆H₁₉N₉O₂
	N-2-(2-Chlorophenyl)sulfanyl-1-(1-cyclohexen-1-yl)ethyl-1-propanamine	309.896	361.176	[M + Cl]^-	6.5	0.2	C₁₇H₂₄NOCl
	2-Hydroxyethyl(tetradecan-2-yl) azanium-chloride	293.92	293.253	[M-H]^-	−0.5	−2.5	C₁₉H₃₃O₂
	4-(Z)-Hexadec-9-enoyl-amino-butyl dihydrogen phosphate	405.516	361.177	[M-P]^-	2.5	−2.1	C₂₀H₄₀NO₅P

Lipid derivatives	3-Acetyl-(2R)-6-methylhept-5-en-2-yl-amino-propyl-dimethylazanium	255.426	255.243	[M-H]^-	5.0	4.6	C₁₅H₃₁NO₂
	Dibutoxy(dihydroxy)phosphanium	211.218	405.262	[M-P]^-	0.5	2.2	C₈H₂₀O₄P
	2-Octyl-1-cyclopropene-1-octanoate (Sterculate)	293.471	293.248	[M-H]^-	4.0	−1.4	C₁₉H₃₃O₂
	Vesnarinone	405.53	405.54	[M-H]^-	1.5	5.0	C₂₂H₃₅N₃O₄

Purine derivatives	2-N-(4-Aminocyclohexyl)-6-N-benzyl-9-cyclopentylpurine-2,6-diamine	405.55	405.263	[M-H]^-	12.5	−1.3	C₂₃H₃₁N₇
Purine derivatives	2-trans-(4-Aminocyclohexyl) amino-6-(benzyl-amino)-9-cyclopentylpurine	405.55	405.263	[M-H]^-	7.0	−1.4	C₂₄H₃₇O₅

Pyrimidine derivatives	Amino-(4-benzamidoanilino) methylidene-(4,6 dimethylpyrimidin-2-yl) azanium	361.429	361.177	[M-H]^-	7.5	2.0	C₂₀H₂₁N₆O
	(2S)-4-(1-Methylpyrrole-2-carbonyl)-N-(3S)-2-oxopiperidin-3-yl]-1-(piperidin-1-ium-4-carbonyl) piperazine-2-carboxamide	445.544	445.255	[M-H]^-	2.0	−0.4	C₂₂H₃₃N₆O₄
	N-(3-Chloro-4-methylphenyl)-6-(4-ethyl-1-piperazinyl) methyl-1,3,5-triazine-2,4-diamine	361.878	293.247	[M + Cl]^-	9.5	0.4	C₁₇H₂₄N₇Cl

Vitamin B	2-4-Amino-6-(3S)-3-methylpiperidin-1-yl-5-nitropyrimidin-2-yl-amino-acetate	309.306	309.130	[M-H]^-	8.0	2.3	C₂H₁₇N₆O₄

Quinolinone derivative	1R,9aR-1,2,3,4,5,6,7,8,9,9a-Decahydroquinolizin-5-ium-1-yl-methoxy-methyl-pentoxy-sulfanylidene-lambda-5-phosphane-chloride	405.539	405.262	[M + CI]^-	10.0	0.9	C₁₆H₃₃NO₂PSCl