Oridonin Attenuates Lipopolysaccharide-Induced ROS Accumulation and Inflammation in HK-2 Cells

Figure 8

Anti-inflammation and antifibrotic mechanisms of oridonin. Oridonin preconditioning exhibited protective effects on LPS-induced iNOS expression, ROS accumulation, JNK phosphorylation, and NF-κB nuclear translocation, COX-2, a-SMA, and CTGF expression in HK-2 cells.