Xiao’er Xiaoji Zhike Oral Liquid Combined with Azithromycin for Mycoplasma pneumoniae Pneumonia in Children: A Systematic Review and Meta-Analysis

Table 1

Basic characteristics of included studies.

Study		Size T/C	Sex male/female	Age		Interventions		Course duration	Outcome measures
				T	C	T	C
Chen [11]		66/66	69/63	6.5 ± 2.4	6.4 ± 2.5	XXZ + Azithromycin, p.o.	Azithromycin, p.o.	10 days	①②③④⑥⑧
Gu [12]		56/56	84/28	7.1 ± 1.0	6.8 ± 1.1	XXZ + Azithromycin, p.o.	Azithromycin, p.o.	1 week	④⑥
Hu [13]		86/86	83/89	8.25 ± 3.71	8.31 ± 2.55	XXZ + Azithromycin, p.o.	Azithromycin, p.o.	4 weeks	①②③④⑦⑧
Qi [14]		34/34	42/26	4.6 ± 1.9	4.8 ± 2.2	XXZ + Azithromycin, p.o.	Azithromycin, p.o.	1 week	④
Wang [15]		32/32	31/33	7.54 ± 2.75	6.32 ± 2.14	XXZ + Azithromycin, p.o.	Azithromycin, p.o.	1 week	④
Xie [16]		60/60	61/59	5.19 ± 2.38	5.21 ± 2.46	XXZ + Azithromycin, p.o.	Azithromycin, p.o.	1 week	④⑥
Yu [17]		31/31	30/32	6.32 ± 2.12	6.94 ± 2.76	XXZ + Azithromycin, p.o.	Azithromycin, p.o.	1 week	④
Xue [18]		46/46	55/37	5.41 ± 1.10	5.38 ± 1.25	XXZ + Azithromycin, p.o.	Azithromycin, p.o.	2 weeks	①②③④⑤⑥⑧
Chao [19]		52/52	62/42	5.27 ± 1.32	5.13 ± 1.26	XXZ + Azithromycin, i.v.	Azithromycin, i.v.	2 weeks	④⑦
Li [20]		36/35	39/32	6.6 ± 2.5	6.2 ± 2.1	XXZ + Azithromycin, i.v.	Azithromycin, i.v.	2 weeks	①②③④⑤
Li [21]		78/76	82/72	5.6 ± 1.3	5.5 ± 1.2	XXZ + Azithromycin, i.v.	Azithromycin, i.v.	2 weeks	④⑦
Li and Jin [22]		63/63	70/56	5.6 ± 1.3	5.5 ± 1.2	XXZ + Azithromycin, i.v.	Azithromycin, i.v.	1 week	④⑦
Zhao [23]		35/35	39/31	7.55 ± 2.06	7.51 ± 2.02	XXZ + Azithromycin, i.v.	Azithromycin, i.v.	2 weeks	①②③④⑤⑧
Zheng et al. [24]		30/30	31/29	8.01 ± 2.32	8.47 ± 2.06	XXZ + Azithromycin, i.v.	Azithromycin, i.v.	30 days	④⑥⑧
Zong [25]		47/46	51/42	3.27 ± 0.77	3.19 ± 0.68	XXZ + Azithromycin, i.v.	Azithromycin, i.v.	15 days	①②③④⑤

XXZ, Xiao’er Xiaoji Zhike oral liquid; T, trial group; C, control group; ①cough disappearance time, ②lung rale disappearance time, ③fever subsidence time, ④total effective rate, ⑤lung X-ray infiltrates disappearing time, ⑥immunological indexes, ⑦others, and ⑧adverse reaction.