Extract of Pogostemon cablin Possesses Potent Anticancer Activity against Colorectal Cancer Cells In Vitro and In Vivo

Table 1

The IC₅₀ values of PCa against CRC and normal cells.

Cell line	Tumor type	PCa	5-FU
HT-29	Human colorectal adenocarcinoma	21.04 ± 0.68^a,b	8.60 ± 1.52
CT26	Mouse colon carcinoma	15.46 ± 1.28^a,b	0.3 ± 0.01
SVEC	Mouse endothelia cell	40.35 ± 2.91^a	<6.25
MDCK	Canine kidney epithelial cell	68.55 ± 0.28^a	12.30 ± 1.53

Note. Values are expressed as mean ± SD (μg/ml) at 48 h. ^aA significant difference between the PCa group compared with the 5-FU group. ^bA significant difference between the CRC cells compared with normal cells.