Orlistat-Induced Gut Microbiota Modification in Obese Mice

Figure 5

Bacterial co-occurrence network analysis associated with high-fat diet and orlistat treatment. Each node in the network represents one of the 9 highest bacteria and the size of each node represents its relative abundance. Edges indicate the bacterial connections expressed Spearman’s correlation coefficients with values greater than cut-off of 0.7 and adjusted value less than 0.05. Positive and negative correlations are shown in red and blue edges, respectively. (a) NCD co-occurrence network. (b) HFD co-occurrence network. (c) HFD + ORL co-occurrence network