Research Article

Analysis of Influencing Factors of Compliance with Non-Vitamin K Antagonist Oral Anticoagulant in Patients with Nonvalvular Atrial Fibrillation and Correlation with the Severity of Ischemic Stroke

Table 2

Univariate analysis of influencing compliance with NOACs (n, %, ).

Clinical informationGood compliance group (n = 59)Poor compliance group (n = 87)χ2/t

Gender
 Male35 (59.3)50 (57.5)0.0500.824
 Female24 (40.7)37 (42.5)

Age
 <65 years41 (69.5)40 (75.5)7.8700.001
 ≥65 years18 (30.5)47 (72.3)

Educational background
 No educational background/primary school28 (47.5)18 (20.7)16.350≤0.001
 Middle school/high school18 (30.5)40 (46.0)
 University or above9 (15.3)33 (37.9)

Place of residence
 Rural area49 (83.1)18 (20.7)55.062≤0.001
 Cities and towns10 (16.9)69 (79.3)

Marriage situation
 Unmarried/widowed36 (61.0)33 (37.93)7.5180.006
 Married23 (29.87)54 (70.13)

Smoking history
 Yes25 (42.4)26 (29.9)2.4120.120
 No34 (57.6)61 (70.1)

Drinking history
 Yes18 (30.5)33 (37.9)0.8520.356
 No41 (69.5)54 (62.1)
Number of complications2.6 ± 1.43.1 ± 0.92.6270.012
Number of concomitant medications4.3 ± 2.14.6 ± 2.20.8230.412

CHA2DS2-VASc score
 <2/3 (male/female)40 (67.80)5 (5.75)63.484≤0.001
 ≥2/3 (male/female)19 (32.20)82 (94.25)

HAS-BLED score
 <3 score51 (86.44)16 (18.39)49.313≤0.001
 ≥3 score8 (13.56)51 (58.62)