Exploring the Potential Mechanism of Tang-Shen-Ning Decoction against Diabetic Nephropathy Based on the Combination of Network Pharmacology and Experimental Validation

Table 1

The potential bioactive compounds in TSN.

Mol ID	Compounds	OB	DL	Herb
MOL000211	Mairin	55.38	0.78	HQ
MOL000239	Jaranol	50.83	0.29	HQ
MOL000296	Hederagenin	36.91	0.75	HQ
MOL000033	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R,5S)-5-propan-2-yloctan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol	36.23	0.78	HQ
MOL000354	Isorhamnetin	49.6	0.31	HQ
MOL000371	3,9-Di-O-methylnissolin	53.74	0.48	HQ
MOL000374	5′-Hydroxyiso-muronulatol-2′,5′-di-O-glucoside	41.72	0.69	HQ
MOL000378	7-O-Methylisomucronulatol	74.69	0.3	HQ
MOL000379	9,10-Dimethoxypterocarpan-3-O-β-D-glucoside	36.74	0.92	HQ
MOL000380	(6aR,11aR)-9,10-Dimethoxy-6a,11a-dihydro-6H-benzofurano [3,2-c]chromen-3-ol	64.26	0.42	HQ
MOL000387	Bifendate	31.1	0.67	HQ
MOL000392	Formononetin	69.67	0.21	HQ
MOL000398	Isoflavanone	109.99	0.3	HQ
MOL000417	Calycosin	47.75	0.24	HQ
MOL000422	Kaempferol	41.88	0.24	HQ, JYZ
MOL000433	FA	68.96	0.71	HQ, CX
MOL000438	(3R)-3-(2-Hydroxy-3,4-dimethoxyphenyl)chroman-7-ol	67.67	0.26	HQ
MOL000439	Isomucronulatol-7,2′-di-O-glucosiole	49.28	0.62	HQ
MOL000442	1,7-Dihydroxy-3,9-dimethoxy pterocarpene	39.05	0.48	HQ
MOL000098	Quercetin	46.43	0.28	HQ, JYZ
MOL002773	Beta-carotene	37.18	0.58	QS
MOL007180	Vitamin-E	32.29	0.7	QS
MOL001494	Mandenol	42	0.19	JYZ, CX
MOL000358	Beta-sitosterol	36.91	0.75	JYZ, DH
MOL005030	Gondoic acid	30.7	0.2	JYZ
MOL008622	Methyl trametenolate	42.88	0.82	JYZ
MOL008628	4′-Methyl-N-methylcoclaurine	53.43	0.26	JYZ
MOL002280	Torachrysone-8-O-beta-D-(6′-oxayl)-glucoside	43.02	0.74	DH
MOL002281	Toralactone	46.46	0.24	DH
MOL002288	Emodin-1-O-beta-D-glucopyranoside	44.81	0.8	DH
MOL002293	Sennoside D_qt	61.06	0.61	DH
MOL002297	Daucosterol_qt	35.89	0.7	DH
MOL002303	Palmidin A	32.45	0.65	DH
MOL000471	Aloe-emodin	83.38	0.24	DH
MOL000554	Gallic acid-3-O-(6′-O-galloyl)-glucoside	30.25	0.67	DH
MOL000096	(−)-Catechin	49.68	0.24	DH
MOL002135	Myricanone	40.6	0.51	CX
MOL002140	Perlolyrine	65.95	0.27	CX
MOL002151	Senkyunone	47.66	0.24	CX
MOL002157	Wallichilide	42.31	0.71	CX
MOL000359	Sitosterol	36.91	0.75	CX
MOL002235	Eupatin	50.8	0.41	DH
MOL002251	Mutatochrome	48.64	0.61	DH
MOL002259	Physciondiglucoside	41.65	0.63	DH
MOL002260	Procyanidin B-5,3′-O-gallate	31.99	0.32	DH
MOL002268	Rhein	47.07	0.28	DH
MOL002276	Sennoside E_qt	50.69	0.61	DH