The Use of Essential Oils and Their Isolated Compounds for the Treatment of Oral Candidiasis: A Literature Review

Table 5

In vitro antifungal activity of phytoconstituents isolated from essential oils against Candida spp. strains.

Plant species	Source	Microorganism	MIC (μg/mL)	MFC (μg/mL)	Score MIC	Ref.
Citral	Commercial source	Candida albicans ATCC 76645	32	32	++++	[34]
		Clinical isolates Candida albicans	32–64	32–64	++++
Linalol	Commercial source	C. albicans CA 032	2000	2000	+	[35]
		Candida albicans 051	1000	2000	+
		Clinical isolate Candida tropicalis	500	500	+++
		Clinical isolates Candida krusei	2000	2000	+
α-Pinene	Leaves	Candida albicans clinical strain	500	>2001	++	[21]
Terpinen-4-ol	Commercial source	Clinical isolates C. albicans	>2001	nt	−	[31]
γ-Terpinene	Leaves	Candida albicans clinical strain	>2001	>2001	−	[21]
Thymol	Commercial source	C. albicans CBS 562	39	39	++++	[36]
		C. tropicalis CBS 94	78	78	++++
		C. krusei CBS 573	39	39	++++

Note: comparative MIC values (μg/mL): (++++) <100; (+++) 100 to 500; (++) 501 to 1000; (+) >1001 to 2000; (−) >2001.