In Vivo Antimalarial Activity and Toxicity Study of Extracts of Tagetes erecta L. and Synedrella nodiflora (L.) Gaertn. from the Asteraceae Family
Table 2
Effects of the T. erecta aqueous extract and S. nodiflora ethanolic extract on the biochemical parameters of liver and kidney function in the acute toxicity test.
Group
Liver function test
AST (U/L)
ALT (U/L)
ALP (U/L)
Untreated control
124.06 ± 8.53
37.20 ± 2.77
97.31 ± 6.99
7% Tween 80
128.30 ± 4.85
33.75 ± 3.56
98.52 ± 4.51
T. erecta extract
125.56 ± 10.75
32.30 ± 5.53
101.58 ± 6.21
S. nodiflora extract
120.03 ± 7.26
33.78 ± 3.42
91.38 ± 2.36
Group
Kidney function test
BUN (mg/dL)
BUN (mg/dL)
Untreated control
23.94 ± 0.44
0.54 ± 0.03
7% Tween 80
22.27 ± 1.30
0.56 ± 0.03
T. erecta extract
23.78 ± 0.93
0.54 ± 0.01
S. nodiflora extract
22.22 ± 0.72
0.56 ± 0.01
The data are presented as the means ± SEMs (n = 5 per group), .
