Research Article
Quercetin Improves Mitochondrial Function and Inflammation in H2O2-Induced Oxidative Stress Damage in the Gastric Mucosal Epithelial Cell by Regulating the PI3K/AKT Signaling Pathway
Figure 4
Que improves H2O2-induced oxidative stress damage in GES-1 cells by regulating the PI3K/AKT signaling pathway. Flow cytometry was performed to evaluate the proportion of (a) cells with increase in ROS and (b) apoptotic cells. (c) The representative ultrastructure of mitochondria in GES-1 cells (12.0 K). Western blot was performed to detect the (d) the phosphorylation of DRP1 and the expression of MFN2 and (e) PI3K/AKT signaling pathway-related protein expression in GES-1 cells. Data presets as mean ± SD, n = 3, ∗P < 0.05.
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