Renal Denervation Mitigated Fecal Microbiota Aberrations in Rats with Chronic Heart Failure

Table 1

Significance tests on community structures between groups with MRPP, AMOVA, ANOSIM, and ADONIS tests.

Groups	MRPP		AMOVA	ANOSIM		ADONIS
	A			R		R^2
Control vs. HF	0.04	0.026	0.095	0.42	0.012	0.17	0.020
Control vs. RDN	−0.00	0.471	0.603	0.04	0.536	0.10	0.567
Control vs. NEP	0.05	0.056	0.348	0.17	0.16	0.18	0.084
Control vs. Nog	0.02	0.148	0.071	0.15	0.167	0.13	0.168
HF vs. RDN	0.07	0.003	0.015	0.48	0.006	0.21	0.008
HF vs. NEP	0.09	0.002	0.010	0.63	0.001	0.24	0.001
HF vs. Nog	0.10	0.002	0.001	0.61	0.002	0.25	0.001
RDN vs. NEP	0.03	0.077	0.315	0.14	0.167	0.14	0.126
RDN vs. Nog	−0.00	0.433	0.585	0.05	0.279	0.08	0.540
NEP vs. Nog	0.05	0.008	0.170	0.24	0.026	0.16	0.015

Bold values indicate statistical significance (). “A” values in the MRPP test greater than 0 indicated that the intergroup difference is greater than the intragroup difference, but “A” values less than 0 indicated that the intragroup difference is greater than intergroup difference. In the ANOSIM test, R > 0 indicated that the differences between the groups were larger than the differences within the groups. The larger R² value in the ADONIS test indicated a better explanation for the classified difference. MRPP: multiresponse replacement process; AMOVA: analysis of molecular variance; ANOSIM: analysis of similarity; ADONIS: analysis of distance matrices.