Research Article

Zanthoxylum bungeanum Seed Oil Attenuates LPS-Induced BEAS-2B Cell Activation and Inflammation by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway

Figure 3

ZBSO inhibited the mRNA expression of LPS-stimulated proinflammatory factors. BEAS-2B cells were pretreated with ZBSO (0.025%, 0.05%, or 0.1% v/v) for 4 h and then treated with LPS (100 ng/mL) for 24 h. The results showed that ZBSO significantly inhibited LPS induction of TNF-α (a), IL-6 (b), IL-10 (c), MCP-1 (d), MMP-2 (e), and MMP-9 (f) expression. The experiment was repeated three times. The results are expressed as the mean ± SD; and versus the control group; and versus the LPS group.
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