Research Article

Identification of Potential Biomarkers of Depression and Network Pharmacology Approach to Investigate the Mechanism of Key Genes and Therapeutic Traditional Chinese Medicine in the Treatment of Depression

Table 2

Molecular docking score.

TargetPDB IDCompoundAffinity (kJ·mol−1)

JUNP05412Luteolin−8.8
Quercetin−8.6
Kaempferol−8.4
Beta-sitosterol−6.8
MAPK8P45983Kaempferol−5.5
RELAP9WHG9Isorhamnetin−7.6
Quercetin−7.5
Arachidonic acid−5
TP53Q96S44Luteolin−8.2
Quercetin−8
RB1P13405Quercetin−8.4
Luteolin−8.9
MAPK14Q16539Petunidin−9
Isorhamnetin−9
CCND1P24385Quercetin−7.1
Arachidonic acid−4.9
Luteolin−7.3
MAPK1P28482Quercetin-8.4
Arachidonic acid−5.8
Luteolin−8.5
AKT1P31750Luteolin−6.3
Quercetin−6.3
Kaempferol−6.4
HSP90AA1P07900Kaempferol−6.7
Beta-sitosterol−7.4
(+)-Catechin−6.8
Isorhamnetin−6.9
Cubebin−6.7
Quercetin−6.9
ESR1P03372(+)-Catechin−7.1
Isorhamnetin−8.5