Antimalarial Property and Acute Toxicity of the Leaves of Theobroma cacao L.
Table 2
Parasitaemia levels and percentage parasitaemia suppression in P. berghei-infected mice.
Dose (mg/kg/day)
Parasitaemia (%) on day 3 after the infection
Parasitaemia (%) on day 7 after the infection
% suppression
100
66.12 ± 6.36
34.51 ± 5.50a
59.98 ± 6.05a
200
65.41 ± 4.17
21.01 ± 1.95a
67.52 ± 1.68a
400
64.43 ± 3.89
17.97 ± 3.36a
79.16 ± 3.90a
NC
69.68 ± 4.20
86.23 ± 2.18
NS
PC
66.43 ± 6.98
11.75 ± 1.19a
86.37 ± 0.61a
Values were presented as mean ± SEM; n = 4; NC = vehicle-treated group; Ar = artesunate; NS = no suppression. Values are significantly different at p < 0.0001.