Antimalarial Property and Acute Toxicity of the Leaves of Theobroma cacao L.

Table 2

Parasitaemia levels and percentage parasitaemia suppression in P. berghei-infected mice.

Dose (mg/kg/day)	Parasitaemia (%) on day 3 after the infection	Parasitaemia (%) on day 7 after the infection	% suppression
100	66.12 ± 6.36	34.51 ± 5.50^a	59.98 ± 6.05^a
200	65.41 ± 4.17	21.01 ± 1.95^a	67.52 ± 1.68^a
400	64.43 ± 3.89	17.97 ± 3.36^a	79.16 ± 3.90^a
NC	69.68 ± 4.20	86.23 ± 2.18	NS
PC	66.43 ± 6.98	11.75 ± 1.19^a	86.37 ± 0.61^a

Values were presented as mean ± SEM; n = 4; NC = vehicle-treated group; Ar = artesunate; NS = no suppression. Values are significantly different at ^p < 0.0001.