Research Article

The Effect of Toothpastes Containing Natural Ingredients Such As Theobromine and Caffeine on Enamel Microhardness: An In Vitro Study

Table 2

Enamel microhardness values after brushing in each four groups.

GroupHardness mean value ± SD (KHN) value
Demineralization hardness ± SDRemineralization hardness ± SDDiff 2 ± SD

1 (theobromine)151.09 ± 82.76289.34 ± 100.55138.24 ± 110.890.001
2 (caffeine)151.20 ± 64.03231.05 ± 49.8279.84 ± 56.860.001
3 (fluoride)146.29 ± 69.26291.82 ± 94.51145.53 ± 84.430.001
4 (distilled water)149.98 ± 64.42209.15 ± 57.2459.16 ± 53.380.001
0.9960.0040.003

Diff 2 = remineralization–demineralization; SD: standard deviation.