Research Article
Pharmacodynamic Evaluation of the Gexia Zhuyu Decoction in the Treatment of NAFLD and the Molecular Mechanism Underlying the TRPM4 Pathway Regulation
Table 2
Serum biochemical indicators after Gexia Zhuyu decoction administration.
| nmol/L | NAFL | NASH | Nonalcoholic fatty liver fibrosis | CG | CG + GXZY | MG | GXZY | CG | CG + GXZY | MG | GXZY | CG | CG + GXZY | MG | GXZY |
| Serum ALT | 50.0 ± 0.05 | 48.32 ± 1.13 | 122.3 ± 8.35 | 95.26 ± 6.03 | 37.35 ± 6.16 | 36.68 ± 5.58 | 235.57 ± 7.32 | 202.11 ± 7.39 | 39.32 ± 1.45 | 42.05 ± 1.62 | 224.51 ± 18.16 | 127.53 ± 10.12 | Serum AST | 105.55 ± 5.30 | 103.26 ± 4.83 | 196.28 ± 3.47 | 165.52 ± 5.02 | 105.63 ± 6.49 | 108.05 ± 6.37 | 298.51 ± 11.16 | 254.53 ± 10.12 | 86.35 ± 9.16 | 84.68 ± 5.58 | 285.57 ± 15.32 | 152.11 ± 7.39 | Serum TG | 0.73 ± 0.12 | 0.75 ± 0.09 | 1.75 ± 0.08 | 1.23 ± 0.16 | 0.91 ± 0.21 | 0.89 ± 0.22 | 1.97 ± 0.13 | 1.45 ± 0.14 | 0.95 ± 0.21 | 0.91 ± 0.24 | 0.57 ± 0.17 | 0.78 ± 0.25 | Liver TG | 0.85 ± 0.12 | 0.82 ± 0.09 | 1.65 ± 0.29 | 1.12 ± 0.06 | 0.85 ± 0.12 | 0.82 ± 0.09 | 2.05 ± 0.08 | 1.69 ± 0.16 | 3.23 ± 0.30 | 3.57 ± 0.32 | 7.59 ± 0.34 | 5.41 ± 0.25 |
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Compared to the model group, ∗∗, ∗. |