Tanshinone IIa Induces Autophagy and Apoptosis via PI3K/Akt/mTOR Axis in Acute Promyelocytic Leukemia NB4 Cells

<div>TanIIa-induced NB4 apoptosis. (a) Giemsa staining of NB4 cells treated with TanIIa for 24 h. (b) Annexin V/PI staining of NB4 cells treated with TanIIa for 24 h. (c) The western blotting of apoptotic proteins in NB4 cells treated with TanIIa for 24 h. (d) The relative quantification of apoptotic proteins in NB4 cells treated with TanIIa for 24 h. 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Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Tanshinone IIa Induces Autophagy and Apoptosis via PI3K/Akt/mTOR Axis in Acute Promyelocytic Leukemia NB4 Cells 