Research Article

Network Pharmacology Study on Molecular Mechanisms of Zhishi Xiebai Guizhi Decoction in the Treatment of Coronary Heart Disease

Table 1

Effective components of Zhishi Xiebai Guizhi Decoction that meet the demands of both OB ≥ 30% and DL ≥ 0.18 were obtained from TCMSP.

DrugIDComponentsOB%DL

GLMOL001494Mandenol41.99620.19321
MOL002881Diosmetin31.137950.27442
MOL004355Spinasterol42.979370.75534
MOL005530Hydroxygenkwanin36.4670.27206
MOL006756Schottenol37.423120.75067
MOL00716510α-cucurbita-5,24-diene-3β-ol44.015940.7445
MOL0071715-Dehydrokarounidiol30.226650.7703
MOL0071727-Oxo-dihydrokaro-unidiol36.850210.75387
MOL007175Karounidiol 3-o-benzoate43.990610.49505
MOL007179Linolenic acid ethyl ester46.100960.19694
MOL007180Vitamin-e32.286430.69563

HPMOL005970Eucalyptol60.624760.32159
MOL005980Neohesperidin57.440740.27085

GZMOL000073Ent-epicatechin48.959840.24162
MOL000358Beta-sitosterol36.913910.75123
MOL000359Sitosterol36.913910.7512
MOL000492(+)-catechin54.826430.24164
MOL001736(−)-Taxifolin60.506220.27342

XBMOL000098Quercetin46.433350.27525
MOL000332n-coumaroyltyramine85.628830.20287
MOL000358Beta-sitosterol36.913910.75123
MOL000483(Z)-3-(4-Hydroxy-3-methoxy-phenyl)-N-[2-(4-hydroxyphenyl) ethyl] acrylamide118.34770.26399
MOL000631Coumaroyltyramine112.90160.20234
MOL001973Sitosteryl acetate40.389640.85102
MOL002341Hesperetin70.312090.27252
MOL004328Naringenin59.29390.21128
MOL007640Macrostemonoside e_qt35.2590.87216
MOL007650PGA (sup 1)43.982510.25437
MOL007651Prostaglandin B140.207770.25384

ZSMOL000006Luteolin36.162630.24552
MOL001798Neohesperidin_qt71.168860.27085
MOL001803Sinensetin50.556850.44634
MOL001941Ammidin34.548560.22355
MOL002914Eriodyctiol (flavanone)41.350430.2436
MOL004328Naringenin59.29390.21128
MOL0051005,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl) chroman-4-one47.736440.27226
MOL005828Nobiletin61.669440.51652
MOL005849Didymin38.551390.23908
MOL007879Tetramethoxyluteolin43.684760.37009
MOL0090534-[(2S,3R)-5-[(E)-3-Hydroxyprop-1-enyl]-7-methoxy-3-methylol-2,3-dihydrobenzofuran-2-yl]-2-methoxy-phenol50.755140.3948
MOL013276Poncirin36.546010.74202
MOL013277Isosinensetin51.151690.44149
MOL0132795,7,4′-Trimethylapigenin39.832720.29636
MOL013352Obacunone43.286250.76724
MOL013428Isosakuranetin-7-rutinoside41.240130.71616
MOL013430Prangenin43.597340.29428
MOL013433Prangenin hydrate72.634010.28863
MOL013435Poncimarin63.620930.34942
MOL013436Isoponcimarin63.27760.31316
MOL0134376-Methoxy aurapten31.237770.3008
MOL013440Citrusin B40.797170.71331