Research Article
Network Pharmacology Study on Molecular Mechanisms of Zhishi Xiebai Guizhi Decoction in the Treatment of Coronary Heart Disease
Table 2
Top 20 targets of Zhishi Xiebai Guizhi Decoction in the treatment of coronary heart disease.
| | UniP-ID | Protein names | Degree |
| | P03372 | Estrogen receptor (ESR1) | 41 | | P10275 | Androgen receptor (AR) | 40 | | P35354 | Prostaglandin G/H synthase 2 (PTGS2) | 35 | | P37231 | Peroxisome proliferator activated receptor gamma (PPARG) | 32 | | P27487 | Dipeptidyl peptidase IV (DPP4) | 32 | | P35228 | Nitric oxide synthase, inducible (NOS2) | 30 | | P23219 | Prostaglandin G/H synthase 1 (PTGS1) | 28 | | P49841 | Glycogen synthase kinase-3 beta (GSK3B) | 28 | | Q16539 | Mitogen-activated protein kinase 14 (MAPK14) | 27 | | P24941 | Cell division protein kinase 2 (CDK2) | 27 | | P20248 | Cyclin-A2 (CCNA2) | 26 | | P00918 | Carbonic anhydrase II (CA2) | 26 | | P18031 | mRNA of protein-tyrosine phosphatase, nonreceptor type 1 (PTPN1) | 23 | | P11309 | Protooncogene serine/threonine-protein kinase Pim-1 (PIM1) | 23 | | P00734 | Thrombin (F2) | 22 | | P0DP23 | Calmodulin (CALM1) | 17 | | P48736 | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform (PIK3CG) | 15 | | Q14524 | Sodium channel protein type 5 subunit alpha (SCN5A) | 14 | | P07550 | Beta-2 adrenergic receptor (ADRB2) | 14 | | P00742 | Coagulation factor Xa (F10) | 9 |
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