Research Article
The Aqueous Extract of Eucommia Leaves Promotes Proliferation, Differentiation, and Mineralization of Osteoblast-Like MC3T3-E1 Cells
Table 6
Gene list of osteoblast markers (ELAE vs. Blank).
| | Gene name | Blank (FPKM) | ELAE (FPKM) | log2 fold change (ELAE/Blank) | p value |
| | Collagen, type V, alpha 2 (Col5a2) | 126.18 | 153.83 | 0.29 | 2.32E − 38 | | Ubiquitin-associated protein 2-like (Ubap2l) | 68.00 | 80.93 | 0.25 | 3.22E − 10 | | Dickkopf WNT signaling pathway inhibitor 3 (Dkk3) | 62.75 | 75.49 | 0.27 | 2.94E − 10 | | Forkhead box M1 (Foxm1) | 48.45 | 55.23 | 0.19 | 1.70E − 05 | | Collagen, type XVI, alpha 1 (Col16a1) | 46.76 | 51.28 | 0.13 | 1.37E − 03 | | Collagen, type XII, alpha 1 (Col12a1) | 20.85 | 25.79 | 0.31 | 4.63E − 14 | | Ubiquitin-specific peptidase 7 (Usp7) | 16.46 | 22.8 | 0.47 | 8.63E − 13 | | Collagen, type IV, alpha 6 (Col4a6) | 12.25 | 16.42 | 0.42 | 1.02E − 09 | | Runt-related transcription factor 2 (Runx2) | 10.05 | 11.43 | 0.19 | 9.47E − 03 | | SRY (sex-determining region Y)-box 4 (Sox4) | 3.91 | 6.85 | 0.81 | 3.14E − 06 | | Bone morphogenetic protein 4 (Bmp4) | 3.40 | 5.17 | 0.60 | 8.98E − 03 |
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