Saireito Improves Lymphatic Function and Prevents UVB-Induced Acute Inflammation and Photodamage in HR-1 Hairless Mice

Figure 3

Effect of SRT on UVB-induced skin thickness and collagen degradation. (a) Skin sections were collected every 24 h after irradiation, and HE staining was performed. (b) SRT had no effect on UVB-induced epidermal hyperplasia. (c) SRT significantly inhibited UVB-induced edema formation at 24 h and 72 h after irradiation. (d) Skin sections were collected at 72 h after irradiation, and Masson’s trichrome staining was performed. (e) SRT significantly attenuated UVB-induced decrease of collagen fibers at 72 h after irradiation. Data were expressed as mean ± SEM (n = 5). Scale bar = 200 μm. and vs. control, Dunnett’s test. vs. vehicle, Student’s t-test. SRT: Saireito extract; UVB: ultraviolet B.

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