Methanolic Extract of Myrsine africana Leaf Ameliorates Hyperglycemia and Dyslipidemia in Alloxan-Induced Diabetic Albino Mice

Table 7

Effect of the repeated daily dose of M. africana methanolic leaf extract on body weight in diabetic mice.

Group	Body weight (gm.)
	Before diabetes induction	Baseline	7^th day of treatment	14^th day of treatment
Diabetic control	24.3 ± 4.1	19.3 ± 4	19.6 ± 3.2 ^nG	15 ± 2.8 ^βF nG
MA 250 mg/kg	23 ± 3.2	18.3 ± 1.8	23 ± 1.2 ^nE	19.6 ± 2.4 ^nG^αE
MA 500 mg/kg	25 ± 1.5	19.3 ± 3	21.6 ± 2.4 ^nF	22.3 ± 2.5 ^nE^αG
MA 1000 mg/kg	23 ± 3.2	18.3 ± 2.8	24.3 ± 2.5 ^αE	22.6 ± 2 ^αG
GLC 5 mg/kg	25 ± 3.5	19.3 ± 2	27.6 ± 1.8 ^αG	26.8 ± 1.4 ^αG
Normal control	23 ± 2.2	21.6 ± 2.1	28 ± 1.8	26.8 ± 2.1

Values are expressed as mean ± SD; n = 6; ^α compared with diabetic control, ⁿ compared with normal control, ^β compared with baseline blood glucose level; ^E, ^F1, ^G; MA, Myrsine africana leaf extract; NS, normal saline; GLC, glibenclamide.