Research Article

Herbal Prescription SH003 Alleviates Docetaxel-Induced Neuropathic Pain in C57BL/6 Mice

Figure 4

Effect of SH003 administration on degeneration of IENF induced by docetaxel. The hind paw skins were isolated and prepared for immunofluorescence staining of IENF in Control (a), Docetaxel (b), and Docetaxel + SH003 (c) groups. The representative images of PGP 9.5-labeled IENF in paw skins were acquired using Zeiss LSM5 PASCAL confocal laser scanning microscope system. White scale bar indicates 50 μm (magnification: 10x). White and yellow arrows indicate the degenerated IENF and stratum lucidum layer, respectively.
(a)
(b)
(c)