Research Article

Ethnobotanical Documentation, Phytochemical Screening, and Cytotoxicity Evaluation of Medicinal Plants Used to Manage Snakebite Envenomation in Mwingi West Subcounty, Kenya

Table 5

Cytotoxic effects of the aqueous, methanolic, and dichloromethane extracts of the selected plants.

DrugLC50 (µg/ml)
Aq.Me.Dc.

E. leptostachya5789.69#∗16108.21#∗ND
S. singueana24995.60#∗230149.13#∗ND
S. longipendunculata170.66##∗∗293.93##∗∗ND
S. henningsii1288.55#∗2180.37#∗ND
Vincristine sulphate4.06##∗∗∗

The superscript notations # and ## represent noncytotoxic and cytotoxic, respectively, based on Clarkson’s criteria, while the superscript notations , ∗∗, and ∗∗∗ represent noncytotoxic, cytotoxic, and highly cytotoxic, respectively based on Meyer’s criteria. ND: not determined. Aq. = aqueous extract; Me. = methanolic extract; Dc: dichloromethane extract.