Antiviral Effect of Hyunggaeyungyo-Tang on A549 Cells Infected with Human Coronavirus

Figure 2

Visualization of PKR and pPKR expression. It used a Zeiss LSM 760 confocal microscope with a C-Apochromat 20x objective lens. Although the difference was not significant, the expression of PKR was increased in the “A549-OC43” than in the “A549-OC43 + drug.” In the case of pPKR, the expression level was significantly increased in the “A549-OC43” than in the “A549-OC43 + drug.” There was no significant difference between the “A549-OC43 + drug” and the “A549-WT” (A549-WT: A549 cells with no treatment; A549-OC43: A549 cells treated with OC43; A549-OC43 + drug: A549 cells treated with OC43 and HGYGT).