Antiviral Effect of Hyunggaeyungyo-Tang on A549 Cells Infected with Human Coronavirus

Table 3

mRNA expression.

mRNA	Expression in control group	Expression in OC43 group ( value vs. control)	Expression in HGYGT group ( value vs. OC43)
OC43		1.019 ± 0.1413	0.4205 ± 0.07611; 0.0102
IL-1	1.002 ± 0.04936	27.75 ± 1.868; <0.0001	21.92 ± 0.6333; 0.0209
TNF-α	1.054 ± 0.2352	225.8 ± 24.08; 0.0004	166.7 ± 8.045; 0.0401
COX-2	1.021 ± 0.1516	10.89 ± 0.8811; 0.0002	8.609 ± 0.3086; 0.0356
NF-κB	1.009 ± 0.09722	6.482 ± 1.039; 0.0032	3.807 ± 0.07861; 0.0311
IFI6	1.026 ± 0.1712	150.5 ± 15.18; 0.0003	84.61 ± 7.541; 0.0089
IFI44	1.071 ± 0.2847	1413 ± 169.2; 0.0006	761.7 ± 49.3; 0.0105
IFI44L	1.009 ± 0.09376	137.1 ± 4.453; <0.0001	98.37 ± 2.426; 0.0008
IFI27	1.002 ± 0.03935	506.2 ± 48.8; 0.0002	328 ± 29.63; 0.0177
IRF7	1.009 ± 0.09585	7.599 ± 0.6307; 0.0002	5.222 ± 0.7767; 0.0382
OASL	1.003 ± 0.05799	86.96 ± 1.575; <0.0001	59.74 ± 2.015; 0.0002
ISG15	1.004 ± 0.06054	71.27 ± 4.874; <0.0001	48.62 ± 4.098; 0.0118
IKK	1.004 ± 0.06449	2.6 ± 0.0503; <0.0001	1.566 ± 0.1109; <0.0001
INOS	1.002 ± 0.04371	2.195 ± 0.05391; <0.0001	1.372 ± 0.02985; <0.0001

Values are presented as mean ± SEM (n = 3) (; ; ; ).