Analysis of the Efficacy and Pharmacological Mechanisms of Action of Zhenren Yangzang Decoction on Ulcerative Colitis Using Meta-Analysis and Network Pharmacology

Table 5

Key target proteins of ZRYZD acting on UC.

Key target	Entry	Entry name	Protein names	Degree
TP53	P04637	P53_HUMAN	Cellular tumor antigen p53	37
VEGFA	P15692	VEGFA_HUMAN	Vascular endothelial growth factor A	35
JUN	P05412	JUN_HUMAN	Transcription factor AP-1	35
CASP3	P42574	CASP3_HUMAN	Caspase-3	34
ESR1	P03372	ESR1_HUMAN	Estrogen receptor	33
PTGS2	P35354	PGH2_HUMAN	Prostaglandin G/H synthase 2	30
MMP9	P14780	MMP9_HUMAN	Matrix metalloproteinase-9	30
PPARG	P37231	PPARG_HUMAN	Peroxisome proliferator-activated receptor gamma	28
BCL2L1	Q07817	B2CL1_HUMAN	Bcl-2-like protein 1	27
CASP8	Q14790	CASP8_HUMAN	Caspase-8	27