UPLC/ESI-MS Phytochemical Screening of Deverra tortuosa Haematological and Histopathological Studies and Streptozotocin-Induced Diabetes in Rat

Table 4

Effects of metformin, insulin, and plant extract on RBC count, Hb concentration, and platelet count in normal and diabetic-treated rats.

Groups	Parameters
	RBC count (10^6/µl)		Hb concentration (g/dl)		Platelet count (10^3/µl)
	Mean ± SE	%	Mean ± SE	%	Mean ± SE	%
Control	7.18 ± 0.16	—	15.83 ± 0.23	—	578 ± 20	—
STZ	3.82 ± 0.003^a	−46.8	14.10 ± 0.03^a	−10	362 ± 0.36^a	−37
STZ + met	7.58 ± 0.003^b	98.4	14.33 ± 0.07^a	1.4	495 ± 16	36.7
STZ + insulin	7.03 ± 0.14^b	84.03	13.77 ± 0.24^a	−2.8	560 ± 17^b	54.7
STZ + herb B	6.90 ± 0.44^b	80.7	14.00 ± 0.48^a	−0.7	339 ± 2.8^a	−6.4

RBC, red blood cell; Hb, hemoglobin. ^aSignificantly different from control at . ^bSignificantly different from STZ at .