Research on the Protective Effect of MiR-185-3p Mediated by Huangqin-Tang Decoction (HQT) on the Epithelial Barrier Function of Ulcerative Colitis

Figure 5

Pattern of regulating the intestinal epithelial barrier by HQT. HQT upregulated miRNA-185-3p expression, thereby inhibiting MLCK expression, further decreasing p-MLC protein and ultimately decreasing cytoskeleton protein contraction, inhibiting cell membrane occludin protein translocation, and promoting increased occludin protein expression.