Research Article
Network Pharmacology and Molecular Docking Suggest the Mechanism for Biological Activity of Rosmarinic Acid
Table 3
Key protein topological parameters of protein interaction network.
| Name | Degree | Betweenness centrality | Closeness centrality |
| TNF | 53 | 0.06924682 | 0.8630137 | IL6 | 51 | 0.05915435 | 0.84 | CASP3 | 49 | 0.08868983 | 0.81818182 | JUN | 46 | 0.03570932 | 0.7875 | MAPK8 | 44 | 0.02681408 | 0.76829268 | IL1B | 42 | 0.01914187 | 0.75 | MMP9 | 42 | 0.02381611 | 0.75 | MAPK3 | 41 | 0.01732055 | 0.74117647 | TLR4 | 40 | 0.01981721 | 0.73255814 | CAT | 38 | 0.07900048 | 0.71590909 | MAPK1 | 38 | 0.0134504 | 0.71590909 | HMOX1 | 36 | 0.01175721 | 0.7 | FN1 | 36 | 0.01346746 | 0.7 | FOS | 34 | 0.02316259 | 0.68478261 | TGFB1 | 34 | 0.03713298 | 0.68478261 | SERPINE1 | 31 | 0.01151125 | 0.66315789 | SOD2 | 30 | 0.03539503 | 0.64948454 | NQO1 | 24 | 0.01251491 | 0.61165049 |
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