Research Article

Network Pharmacology and Molecular Docking Suggest the Mechanism for Biological Activity of Rosmarinic Acid

Table 4

Compound-target molecular docking binding energy.

No.TargetsCompoundBinding energy (kJ/mol)

1MMP9RosA−7.76
2MAPK3−7.71
3JUN−6.83
4CAT−6.68
5SERPINE1−6.61
6MAPK8−6.16
7FN1−6.09
8FOS−6.02
9TGFB1−5.87
10TNF−5.73
11MAPK1−5.57
12TLR4−5.5
13IL1B−5.31
14NQO1−4.76
15CASP3−4.73
16SOD2−4.72
17HMOX1−4.34
18IL6−3.55