Research Article
Hepatoprotective Effect and Potential Mechanism of Aqueous Extract from Phyllanthus emblica on Carbon-Tetrachloride-Induced Liver Fibrosis in Rats
Table 2
AEPE ameliorates CCl4-induced liver fibrosis in rats serum LN, HA, IV-C, and PCIII levels, respectively.
| Groups | LN (ng/mL) | HA (ng/mL) | IV-C (ng/mL) | PCIII (ng/mL) |
| Control | 104.38 ± 4.73 | 82.72 ± 9.44 | 5.48 ± 0.35 | 9.57 ± 1.09 | Model | 156.53 ± 3.51## | 103.64 ± 7.35## | 7.09 ± 0.93## | 12.97 ± 1.44## | AEPE-L | 129.7 ± 11.76 | 94.73 ± 8.30 | 5.79 ± 0.38 | 11.32 ± 0.57 | AEPE-M | 134.72 ± 7.04 | 90.24 ± 5.37 | 5.69 ± 0.39 | 11.21 ± 0.64 | AEPE-H | 126.8 ± 10.76 | 90.49 ± 6.21 | 5.70 ± 0.40 | 11.31 ± 0.66 | Silymarin | 134.38 ± 7.93 | 83.41 ± 6.97 | 5.89 ± 0.40 | 12.06 ± 1.20 |
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Data were expressed as the mean ± SEM ( n = 6–10). vs. control; , vs. model. |