Research Article

Hepatoprotective Effect and Potential Mechanism of Aqueous Extract from Phyllanthus emblica on Carbon-Tetrachloride-Induced Liver Fibrosis in Rats

Table 2

AEPE ameliorates CCl4-induced liver fibrosis in rats serum LN, HA, IV-C, and PCIII levels, respectively.

GroupsLN (ng/mL)HA (ng/mL)IV-C (ng/mL)PCIII (ng/mL)

Control104.38 ± 4.7382.72 ± 9.445.48 ± 0.359.57 ± 1.09
Model156.53 ± 3.51##103.64 ± 7.35##7.09 ± 0.93##12.97 ± 1.44##
AEPE-L129.7 ± 11.7694.73 ± 8.305.79 ± 0.3811.32 ± 0.57
AEPE-M134.72 ± 7.0490.24 ± 5.375.69 ± 0.3911.21 ± 0.64
AEPE-H126.8 ± 10.7690.49 ± 6.215.70 ± 0.4011.31 ± 0.66
Silymarin134.38 ± 7.9383.41 ± 6.975.89 ± 0.4012.06 ± 1.20

Data were expressed as the mean ± SEM (n = 6–10). vs. control; , vs. model.