Research Article
Berbamine Inhibits Cell Proliferation and Migration and Induces Cell Death of Lung Cancer Cells via Regulating c-Maf, PI3K/Akt, and MDM2-P53 Pathways
Figure 9
BBM disrupts the PI3K/Akt and MDM2/p53 signal pathways in tumors. ALB/c mice were untreated (Ctrl) or treated with BBM; the expressions of PI3K (a, b), MDM2 (a, c), p-Akt/Akt (a, d), p53 (a, e), c-Maf (a, f), Bcl-2/Bax (a, g), and cleaved-caspase-3/caspase-3 (a, h) were examined by western blot (nā=ā6). , , and vs. Ctrl group.
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