Research Article
Jian-Gan-Xiao-Zhi Decoction Alleviates Inflammatory Response in Nonalcoholic Fatty Liver Disease Model Rats through Modulating Gut Microbiota
Figure 5
JGXZ treatment increased gut integrity and inhibited the inflammatory response in NAFLD model rats. (a–d) Immunostaining showed that the expression of ZO-1 (a, c) and occludin (b, d) in the colon was increased after JGXZ treatment. (e) The levels of IL-6, IL-1β, and TNF-α in the serum were decreased after JGXZ treatment. (f) The gene expressions of Il6, Il1b, and Tnfa in the liver were decreased after JGXZ treatment. Control, model, JGXZ low-dose, and JGXZ high-dose groups (n = 10 per group). # as compared to the control group; as compared to the control group; ∗ as compared to the experimental model group; as compared to the experimental model group.
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