The Efficacy of Long-Term Chinese Herbal Medicine Use on Lung Cancer Survival Time: A Retrospective Two-Center Cohort Study with Propensity Score Matching
Table 1
Clinical assessment of participants before and after PSM.
Item
Before PSM
value
After PSM
value
CHM group (n = 761)
Control group (n = 373)
CHM group (n = 208)
Control group (n = 208)
Gender
Male
389 (51.1)
246 (66.7)
＜0.001
119 (57.2)
115 (55.3)
0.693
Female
372 (48.9)
128 (34.3)
89 (42.8)
93 (44.7)
Age
≤60
315 (41.4)
186 (49.9)
0.007
91 (43.8)
93 (44.7)
0.843
＞60
446 (58.6)
187 (50.1)
117 (56.2)
115 (55.3)
Pathology
Unspecified
43 (5.7)
1 (0.2)
＜0.001
1 (0.5)
1 (0.5)
0.927
Adenocarcinoma
546 (71.7)
235 (63.0)
151 (72.6)
143 (68.8)
Squamous cell cancer
87 (11.4)
90 (24.1)
33 (15.9)
39 (18.8)
Small cell lung cancer
29 (3.8)
31 (8.3)
12 (5.8)
12 (5.8)
Others
56 (7.4)
16 (4.3)
11 (5.3)
13 (6.3)
Stage
I
295 (38.8)
193 (51.7)
＜0.001
99 (47.6)
93 (44.7)
0.842
II
39 (5.1)
35 (9.4)
18 (8.7)
22 (10.6)
IIIA
47 (6.2)
56 (15.0)
23 (11.1)
29 (13.9)
IIIB
41 (5.4)
51 (13.7)
28 (13.5)
27 (13.0)
IV
339 (44.5)
37 (9.9)
40 (19.2)
37 (17.8)
Surgery
Yes
367 (48.2)
251 (67.3)
＜0.001
134 (64.4)
132 (63.5)
0.838
No
394 (51.8)
122 (32.7)
74 (35.6)
76 (36.5)
Chemotherapy
Yes
337 (44.3)
293 (78.6)
＜0.001
142 (68.3)
128 (60.1)
0.150
No
424 (55.7)
80 (21.4)
66 (31.7)
80 (38.5)
Radiotherapy
Yes
115 (15.1)
70 (18.8)
0.118
37 (17.8)
33 (15.9)
0.600
No
646 (84.9)
303 (81.2)
171 (82.2)
175 (84.1)
Interventional therapy
Yes
9 (1.2)
5 (1.3)
0.821
5 (2.4)
4 (1.9)
0.736
No
752 (98.8)
368 (98.7)
203 (97.6)
204 (98.1)
Targeted therapy
Yes
124 (16.3)
34 (9.1)
0.001
27 (13.0)
24 (11.5)
0.654
No
637 (83.7)
339 (90.9)
181 (87.0)
184 (88.5)
Family history
Yes
207 (27.2)
11 (2.9)
＜0.001
10 (4.8)
11 (5.3)
0.823
No
554 (72.8)
362 (97.1)
198 (95.2)
197 (94.7)
Smoking
Yes
251 (33.0)
99 (26.5)
0.027
63 (30.3)
71 (34.1)
0.401
No
510 (67.0)
274 (73.5)
145 (69.7)
137 (65.9)
Drinking
Yes
77 (10.1)
23 (6.2)
0.027
18 (8.7)
21 (10.1)
0.614
No
684 (89.9)
350 (93.8)
190 (91.3)
187 (89.9)
PSM: propensity score matching; , a significantly statistical difference in subgroup.
