The Efficacy of Long-Term Chinese Herbal Medicine Use on Lung Cancer Survival Time: A Retrospective Two-Center Cohort Study with Propensity Score Matching

Table 3

Cox regression results of lung cancer patients.

Factors	Univariate analysis					Multivariate analysis
	B	Wald		HR	95%CI	B	Wald		HR	95%CI
CHM	−0.327	15.965	＜0.001	0.721	0.614–0.846	−0.774	53.138	＜0.001	0.461	0.375–0.568
Gender	0.852	98.220	＜0.001	2.343	1.980–2.773	0.347	11.359	0.001	1.414	1.156–1.730
Age	0.032	49.518	＜0.001	1.032	1.023–1.042	0.023	25.092	＜0.001	1.024	1.014–1.033
Pathology
Adenocarcinoma	0.036	0.043	0.836	1.036	0.739–1.453
Squamous cell cancer	−0.529	11.382	0.001	0.589	0.433–0.801
Small cell lung cancer	0.185	0.675	0.411	1.204	0.774–1.872
Others as control	NA	78.871	＜0.001	NA	NA
Stage
I as control	NA	269.917	＜0.001	NA	NA	NA	115.146	＜0.001	NA	NA
II	0.663	12.482	＜0.001	1.940	1.343–2.802	0.460	5.868	0.015	1.584	1.092–2.299
IIIA	1.295	80.139	＜0.001	3.650	2.749–4.846	0.882	32.380	＜0.001	2.417	1.783–3.275
IIIB	1.626	130.662	＜0.001	5.084	3.847–6.718	1.072	42.996	＜0.001	2.922	2.121–4.026
IV	1.620	242.732	＜0.001	5.054	4.122–6.197	1.437	112.673	＜0.001	4.208	3.227–5.486
Surgery	−0.997	148.926	＜0.001	0.369	0.314–0.433	−0.448	21.853	＜0.001	0.639	0.530–0.771
Chemotherapy	−0.343	61.861	＜0.001	0.710	0.651–0.773	−0.157	2.437	0.119	0.855	0.702–1.041
Radiotherapy	−0.365	61.164	＜0.001	0.694	0.634–0.761	0.059	0.332	0.564	1.061	0.867–1.298
Interventional therapy	0.458	2.062	0.151	1.581	0.846–2.955
Targeted therapy	−0.339	47.864	＜0.001	0.712	0.647–0.784	−0.140	1.734	0.188	0.870	0.707–1.071
Family history	−0.339	9.413	0.002	0.712	0.574–0.885	0.028	0.059	0.807	1.029	0.820–1.291
Smoking	0.693	70.852	＜0.001	1.999	1.701–2.349	0.192	3.291	0.070	1.212	0.985–1.491
Drinking	0.600	23.410	＜0.001	1.822	1.429–2.323	0.191	1.879	0.170	1.210	0.921–1.589